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PTCB Pharmacy Technician Certification Board

A PTCB Certification board exam is the professional exam validating the skills and knowledge candidates need to work as pharmacy technicians. It tests their knowledge in English, Math, Science (Chemistry) and professional aspects of their job.
Medical Tests Pharmacy Technician Certification Exam Sample Questions (Q64-Q69):
NEW QUESTION # 64
Medications considered to have a narrow therapeutic index generally exhibit a(n):
- A. higher risk of causing serious toxicity.
- B. incompatibility with therapeutic monitoring.
- C. synergistic effect on other medications.
- D. shorter window of guaranteed stability.
Answer: A
Explanation:
ANarrow Therapeutic Index (NTI) drugis a medication in whichsmall differences in dose or blood concentrationcan lead to serioustoxicityorsubtherapeutic effects. These drugs requirecareful dosing and monitoringto avoid adverse effects or treatment failure.
* Small Margin of Safety:The difference between theminimum effective concentration (MEC)and the minimum toxic concentration (MTC)is very narrow.
* Requires Therapeutic Drug Monitoring (TDM):Blood levels of the drug must be regularly monitored to maintain efficacy while avoiding toxicity.
* High Risk of Adverse Effects:Even minor dosage adjustments or variations in patient metabolism can cause toxicity.
* Strict Pharmacokinetic and Pharmacodynamic Considerations:Factors likerenal and hepatic function, drug interactions, and patient weightsignificantly impact the drug's effect.
* Warfarin (Coumadin) # Risk of bleeding.
* Digoxin # Risk of toxicity affecting the heart.
* Phenytoin # Risk of severe neurological effects.
* Levothyroxine # Risk of under- or over-treatment of thyroid disorders.
* Theophylline # Risk of respiratory or cardiac toxicity.
* Carbamazepine # Risk of serious neurological side effects.
* A. Shorter window of guaranteed stability.# Incorrect. NTI drugs do not necessarily have a shorter shelf-life or stability concerns compared to other drugs. Stability depends on formulation and storage conditions.
* B. Incompatibility with therapeutic monitoring.# Incorrect. NTI drugsrequiretherapeutic monitoring, not the opposite.
* C. Synergistic effect on other medications.# Incorrect. While NTI drugs can interact with other drugs, not all exhibit a synergistic effect (where combined drugs produce a greater effect than expected).
* PTCB PTCE Exam Content Outline - Medication Safety and Quality Assurance(Monitoring NTI drugs).
* FDA Narrow Therapeutic Index Drug List(Guidelines on NTI medications).
* Lexicomp and Micromedex Drug Databases(Provide monitoring recommendations for NTI drugs).
* USP <800> Hazardous Drugs and USP <797> Sterile Compounding Guidelines(Ensure safe handling and dispensing of NTI drugs).
* Mosby's Pharmacy Technician: Principles and Practice(NTI drug classification and monitoring).
Key Characteristics of NTI Drugs:Examples of NTI Drugs:Why the Other Answer Choices Are Incorrect:
Pharmacy Technician References:
NEW QUESTION # 65
Colchicineis indicated for the treatment of:
- A. Hyperlipidemia.
- B. Hypothyroidism.
- C. Gout flares.
- D. Peripheral neuropathy.
Answer: C
Explanation:
Comprehensive and Detailed Step-by-Step Explanation:
Colchicine (Colcrys, Mitigare)is used to treatacute gout flaresbyreducing inflammation caused by uric acid crystalsin the joints.
#Explanation of Answer Choices:#B. Gout flares#Correct.Colchicine is ananti-inflammatory drug specific to gout.#A. Hyperlipidemia# Incorrect.Statins are used for hyperlipidemia.#C. Hypothyroidism# Incorrect.Levothyroxine is used for hypothyroidism.#D. Peripheral neuropathy# Incorrect.Gabapentin or pregabalin are used for nerve pain.
#Reference:
* American College of Rheumatology (ACR) Gout Treatment Guidelines
* PTCB Exam: Pharmacology for Technicians
NEW QUESTION # 66
CORRECT TEXT
Novaldex or ________ is an anti-estrogen type medication that is often used in the treatment of breast
cancer.
Answer:
Explanation:
Tamoxifin
NEW QUESTION # 67
CORRECT TEXT
Nausea is not a side effect of.....
Answer:
Explanation:
Loop dieuretics
NEW QUESTION # 68
CORRECT TEXT
If a patient is allergic to penicillin and comes in with a prescription for Keflex, what should you know?
Answer:
Explanation:
The patient might have sensitivity to this medication as well. Notify the registered pharmacist.
NEW QUESTION # 69
......
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