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American Society of Microbiology ABMM Sample Questions (Q59-Q64):
NEW QUESTION # 59
A patient with a history of travel to a tropical region presents with cyclical fevers and chills.Peripheral blood smear reveals the presence of merozoites and schizonts within erythrocytes. The absence of crescent-shaped gametocytes makes Plasmodium falciparum less likely. The MOST probable species is:
- A. Plasmodium malariae
- B. Plasmodium knowlesi
- C. Plasmodium vivax
- D. Plasmodium ovale
Answer: C
NEW QUESTION # 60
Staphylococcus epidermidis, a common cause of healthcare-associated infections, forms biofilms on medical devices. The production of polysaccharide intercellular adhesin (PIA) is a key factor in biofilm maturation.
The expression of PIA is primarily regulated by:
- A. Horizontal gene transfer of the ica operon.
- B. The stringent response pathway activated during nutrient limitation.
- C. A two-component regulatory system involving AgrA and AgrC.
- D. The icaADBC operon, whose expression is influenced by environmental cues.
Answer: D
NEW QUESTION # 61
What is the most appropriate method for sterilizing a heat-labile liquid solution containing essential proteins for use in tissue culture?
- A. Filtration through a 0.22 µm pore size membrane filter
- B. Exposure to ethylene oxide gas
- C. Irradiation with ultraviolet (UV) light
- D. Autoclaving at 121°C for 15 minutes
Answer: A
NEW QUESTION # 62
A patient with a history of travel to a rural area develops a febrile illness with myalgias and thrombocytopenia. Laboratory testing reveals the presence of morulae within circulating leukocytes. The MOST likely diagnosis is:
- A. Lyme disease
- B. Anaplasmosis
- C. Babesiosis
- D. Ehrlichiosis
Answer: D
NEW QUESTION # 63
A research team is investigating the mechanism of bacterial resistance to a novel fluoroquinolone antibiotic.
They isolate a resistant strain of Escherichia coli from a patient with a urinary tract infection. Genetic analysis of this strain reveals a point mutation in the gyrA gene. This mutation MOST likely results in:
- A. Alteration of the DNA gyrase enzyme, reducing its affinity for the fluoroquinolone.
- B. Increased expression of efflux pumps that actively transport the antibiotic out of the cell.
- C. Production of an enzyme that inactivates the fluoroquinolone molecule.
- D. Modification of the ribosomal target site, preventing antibiotic binding.
Answer: A
NEW QUESTION # 64
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